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Dr Matthew J Knight

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Name, qualifications

Dr Matthew J Knight MBE PGCert(Allergy) FRCP

Practising at

West Hertfordshire Teaching Hospitals NHS Trust

Health Education East of England, Cambridge

Specialty

Respiratory Medicine

Sub-specialty

Allergy, General Internal Medicine, Medical Education

Professional Memberships

Clinical Interests

Contact details

Dr Matthew J Knight MBE PGCert(Allergy) FRCP

Consultant Respiratory Physician
West Hertfordshire Hospitals NHS Trust
Watford General Hospital
Dept of Respiratory Medicine – Level 3 PMOK
Vicarage Road
Watford
WD18 0HB
Tel 01923 217 698

Dr Knight can be contacted via the respiratory department – on either 01923 217698 or westherts.respiratory@nhs.net / claire.early@nhs.net

About Dr Knight

Dr Knight has been a consultant at West Herts since 2015 and has an interest in unexplained breathlessness, chronic cough and airways diseases (Asthma, COPD and Bronchiectasis). He regularly performs cardio-pulmonary exercise testing (CPEX) alongside standard clinical assessment. He is actively involved in research and has published widely over recent years, most latterly around Long Covid, out of hospital management of respiratory diseases and the role of technology in remote care of patients. Along with Dr Andy Barlow and colleagues from NHSX he pioneered some of the early work on "Virtual Covid Wards", for which he was awarded an MBE. 

​He qualified from University College London in 2005 and undertook respiratory speciality training in the northwest Thames Respiratory training programme, rotating via the Royal Free, Hammersmith, Royal Brompton, Harefield, Barnet, Northwick Park and Watford General hospitals. He also completed a Postgraduate Certificate in Allergy Medicine at Imperial College London.

He is actively involved with the specialist training and education of junior doctors both locally in Watford and previously at a national level with Health Education England where he was an Associate Postgraduate Dean. He sits as a non-executive director on the board of Penrose Care, a registered provider of home care services in northwest London and is also the Medical Director at Medefer  .

Dr Knight manages patients with a wide range of respiratory problems, but has a particular interest in the following areas of Respiratory Medicine:

Dr Knight works closely with his colleagues in the Chest Clinic as well as colleagues in Respiratory Physiology, Cardiology, Physiotherapy, Speech and Language Therapy, Radiology and Thoracic surgery to ensure that patients treated by him receive the best possible care. 

​Recent publications/media

​Dr Knight’s researchgate and google scholar profiles and links to selected articles and papers:

Virtual wards- an account from NHSX

Feasibility and accuracy of the 40-steps desaturation test to determine outcomes in a cohort of patients presenting to hospital with and without COVID-19

GH Rhys, T Wakeling, SH Moosavi, JP Moore, H Dawes, M Knight, ...
Clinical Medicine 22 (3), 203

Accuracy of Rapid Point-of-Care Antibody Test in patients with suspected or confirmed COVID-19

R Vancheeswaran, ML Willcox, B Stuart, M Knight, H Kandil, A Barlow, ...
Journal of Infection 84 (1), 94-118

Post-acute covid-19 in primary care

M Knight, R Vancheeswaran
bmj 375

Direct and indirect evidence of efficacy and safety of rapid exercise tests for exertional desaturation in Covid-19: a rapid systematic review

A Kalin, B Javid, M Knight, M Inada-Kim, T Greenhalgh
Systematic reviews 10 (1), 1-13

Racial discrepancies in oximetry: where do we stand?

MJ Knight, CP Subbe, M Inada-Kim
Anaesthesia

Early prognostication of COVID-19 to guide hospitalisation versus outpatient monitoring using a point-of-test risk prediction score

F Chua, R Vancheeswaran, A Draper, T Vaghela, M Knight, R Mogal, ...
Thorax 76 (7), 696-703

Ambulatory management of secondary spontaneous pneumothorax: a randomised controlled trial

SP Walker, E Keenan, O Bintcliffe, AE Stanton, M Roberts, J Pepperell, ...
European Respiratory Journal 57 (6)

Authors’ reply to Moyle and Ashworth

M Knight, T Greenhalgh, NJ Fulop, M Inada-Kim
bmj 373

Remote management of covid-19 using home pulse oximetry and virtual ward support

T Greenhalgh, M Knight, M Inda-Kim, NJ Fulop, J Leach, ...
bmj 372

Long Covid- recommendations and priority research questions - a report to the House of Lords Long Covid sub committee. 

Predictors of clinical deterioration in patients with suspected COVID-19 managed in a ‘virtual hospital’setting: a cohort study

NA Francis, B Stuart, M Knight, R Vancheeswaran, C Oliver, M Willcox, ...
BMJ open 11 (3), e045356

P256 Prognostication in COVID-19: a prospectively derived and externally validated risk prediction score for in-hospital death

F Chua, A Draper, M Knight, R Mogal, J Singh, LG Spencer, E Thwaite, ...
Thorax 76 (Suppl 1), A228-A229

Mobile App–Based Remote Patient Monitoring in Acute Medical Conditions: Prospective Feasibility Study Exploring Digital Health Solutions on Clinical Workload During the COVID crisis

SS Shah, A Gvozdanovic, M Knight, J Gagnon
JMIR formative research 5 (1), e23190

Long COVID: a primer for family physicians

T Greenhalgh, M Knight
American family physician 102 (12), 716-717

PMD35 Remote Patient Monitoring in ACUTE Medical Conditions; CAN Digital Health Solutions Reduce Clinician Workload and Ease the Pressure on Healthcare Providers during the Covid Crisis

S Shah, A Gvozdanovic, M Knight, J Gagnon
Value in Health 23, S582

What is the Efficacy and Safety of Rapid Exercise Tests for Exertional Desaturation in Covid-19: A Rapid Systematic Review

A Kalin, B Javid, M Knight, M Inada-Kim, T Greenhalgh

Predictors of adverse outcome in patients with suspected COVID-19 managed in a ‘virtual hospital’setting: a cohort study

NA Francis, B Stuart, M Knight, R Vancheeswaran, C Oliver, M Willcox, ...

Late Breaking Abstract-Randomised trial of ambulatory management of primary spontaneous pneumothorax

R Hallifax, E Mckeown, P Sivakumar, I Fairburn, C Peter, A Leitch, ...
European Respiratory Journal 56 (suppl 64)

Management of post-acute covid-19 in primary care

T Greenhalgh, M Knight, M Buxton, L Husain
bmj 370

Ambulatory management of primary spontaneous pneumothorax: an open-label, randomised controlled trial

RJ Hallifax, E McKeown, P Sivakumar, I Fairbairn, C Peter, A Leitch, ..
The Lancet 396 (10243), 39-49

Randomised Trial for Ambulatory Management of Primary Spontaneous Pneumothorax

R Hallifax, E McKeown, P Sivakumar, I Fairbairn, C Peter, A Leitch, ...
A24. EPIDEMIOLOGY, DIAGNOSIS, AND TREATMENT IN PLEURAL DISEASE AND IP, A1124 …

What is the efficacy and safety of rapid exercise tests for exertional desaturation in covid-19

T Greenhalgh, B Javid, M Knight, M Inada-Kim
Centre for Evidence-Based Medicine, Nuffield Department of Primary Care …

What is the efficacy and safety of rapid exercise tests for exertional desaturation in Covid-19: A rapid review protocol

T Greenhalgh, B Javid, M Knight, M Inada-Kim

The Rocket Pleural Vent in Pneumothorax

M Knight, P Yunger, Z Wu, A Barlow
European Respiratory Journal 54 (suppl 63)

S99 Point of care testing for respiratory viruses (RPOCT): a novel service to facilitate appropriate discharge and infection control measures and improve antimicrobial stewardship

K Roy, K Groom, N Read, C Cucciniello, M Knight
Thorax 73 (Suppl 4), A60-A61

Respiratory viral point of care testing (POCT) allows improved infection control and bed management during an influenza outbreak

K Roy, H Kandil, M Knight, M Thapa, K Groom
European Respiratory Journal 52 (suppl 62)

Point of care respiratory viral testing (POCT): A novel service to target appropriate antimicrobial prescription and improve antibiotic stewardship

K Roy, K Groom, M Knight
European Respiratory Journal 52 (suppl 62)

The role of a pleural service in optimising pleural disease management

M Knight, L Yazbeck, S Hanger, O Butters, D Creer
European Respiratory Journal 44 (Suppl 58)

The effect of bisphosphonates on calcium and parathyroid hormone levels in patients with primary hyperparathyroidism over 2 years

MJ Knight, PJ Hyatt
Endocrine Abstracts 12

¿ Cuál es la eficacia y seguridad de las pruebas rápidas de ejercicio para la desaturación por esfuerzo en covid-19?

B Javid, M Knight, M Inada-Kim

What is the efficacy and safety of rapid exercsie tests for exertional desaturation in covid-19?

T Greenhalgh, B Javid, M Knight, M Inada-Kim

Proof that virtual clinics can reduce waiting lists - HSJ opinion

A Virtual hospital model can help tackle the Covid pandemic - HSJ opinion

Coronavirus patients will need to be monitored for a year - Daily Telegraph newspaper

Everything doctors know so far about treating coronavirus - Daily Telegraph newspaper

Watford General treated hundreds of Covid-19 patients in virtual hospital - Gazette local newspaper

https://www.thehtn.co.uk/2020/06/12/huma-supports-nhsx-remote-monitoring-trials/

https://www.med-technews.com/news/virtual-wards-created-for-remote-monitoring-of-covid-19-pati/

https://www.forbes.com/sites/davidprosser/2020/06/19/huma-proves-the-case-for-digital-health-amid-covid-19-crisis/

https://www.nhsx.nhs.uk/blogs/early-data-nhsx-tech-enabled-remote-monitoring-pilot/

Clinical Trials

https://www.southampton.ac.uk/medicine/academic_units/projects/cerabtc-19.page

https://www.southampton.ac.uk/medicine/academic_units/projects/cerrnatc-19.page

https://www.southampton.ac.uk/medicine/research/projects/covid-19-virtual-hospital-prognostic-study-covpro.page?#project_overview%0A____________________

https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/predict-covid-uk-the-development-of-a-risk-scoring-tool-for-covid-19-covid-19/

Randomised ambulatory management of primary pneumothorax (RAMPP) RAMPP study

(Randomised ambulatory management of primary pneumothorax)

The use of an ambulatory device in treatment of pneumothoraces caused by underlying lung disease

​HiSPEC trial – The use of an ambulatory device in the treatment of pneumothoraces caused by underlying lung disease


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